Product Name | MOTS - cH - MRWQEMGYIFYPRKLR - OH |
Size | 1 mg |
Catalog # | AS-65587 |
US$ | $153 |
Purity | % Peak Area By HPLC ≥ 95% |
Recent advances in high-resolution sequencing have led to the discovery of unique peptides derived from mitochondrial genome.1-2 Currently 8 peptides are identified: humanin, mitochondrial open reading frame of the 12S tRNA-c (MOTS-c), and six small humanin-like peptides (SHLP1-6). 1-2 All of these peptides are released into cytosol from mitochondria and associate with increased longevity and cell viability, reduced apoptosis, and other beneficial functions. 1-3MOTS-c was found to reduce insulin resistance, decrease obesity, and promote homeostasis. 3 | |
Detailed Information | ![]() ![]() |
Storage | -20°C |
References | 1. Cobb L. J. et al., AGING 8 (4), 796-808 (2016). 2. Okada A. K. et al., Sci Reports 7 (7802), 1-10 (2017). 3. Lee C., et al., Cell Met 21, 443-454 (2015). |
Molecular Weight | 2174.7 |
H-MRWQEMGYIFYPRKLR-OH | |
Sequence(Three-Letter Code) | NH2 - Met - Arg - Trp - Gln - Glu - Met - Gly - Tyr - Ile - Phe - Tyr - Pro - Arg - Lys - Leu - Arg -COOH |
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